IBRANCE 125 mg, 3×7, Pfizer

The drug is an anti-cancer drug with the active ingredient palbociclib.
Palbociclib inhibits certain proteins called cyclin-dependent kinases 4 and 6, which control cell growth and division. Blocking these proteins can slow the growth of cancer cells and slow down the progression of cancer.
The drug is used to treat patients with certain types of breast cancer (hormone receptor positive, epidermal growth factor receptor-2 negative breast cancer) when it has spread beyond the original tumor and/or to other organs. It is prescribed with aromatase inhibitors or fulvestrant, which are used as hormone therapy to treat cancer.
contraindication
Medicine cannot be taken
If you are allergic to palbociclib or any of the other ingredients of this medicine.
During the reception should avoid the use of drugs containing St. John’s wort.
Dosage
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose is 125 mg once daily for 3 weeks followed by a 1 week break. Your doctor will tell you how many tablets to take.
If you experience certain side effects while taking it, your doctor may lower your dose or stop treatment temporarily or permanently. The dose may be reduced to one of the other dosages, 100 mg or 75 mg.
If you take more than you should
If you have taken too much, contact your doctor or hospital immediately. You may need urgent treatment.
Take your medicine pack and leaflet with you so your doctor knows what you have taken.
If you forget to take a dose
If you miss a dose or vomit, take your next dose as scheduled. Do not take a double dose to make up for a missed dose.
If you stop taking it
Do not stop treatment unless you have discussed this with your doctor.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
patient records
Warnings and Precautions
Please talk to your doctor, pharmacist or nurse before taking this medicine.
The medicine can decrease your white blood cell count and weaken your immune system. Therefore, when taking it, the risk of infection may increase.
Tell your doctor, pharmacist or nurse if you have symptoms of an infection such as chills or fever.
During treatment, you will have regular blood draws to check for possible effects on your blood cells (white blood cells, red blood cells, and platelets).
The medicine can cause severe or life-threatening pneumonia during treatment, which can lead to death. Tell your doctor or nurse right away if you notice any new or worsening symptoms, such as:
Difficulty breathing or shortness of breath
dry cough
chest pain
children and young people
The drug should not be used in children and adolescents (under 18 years of age).
Ability to drive and use machines
Fatigue is a very common side effect. If you feel unusually tired or fatigued, take extra care when driving or operating machinery.
pregnancy
Do not take the drug if you are pregnant.
You should not get pregnant while taking it.
Discuss appropriate contraceptive measures with your doctor if there is a possibility that you or your partner may become pregnant.
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Women of childbearing age taking this medicine or their male partners must use an effective method of contraception (eg, double barrier methods such as a condom and a diaphragm). Such methods should be used during treatment and for at least 3 weeks (for women) or 14 weeks (for men) after completion of treatment.
lactation
You should not breastfeed while you are taking this medicine. It is not known whether the drug passes into breast milk.
fertility
Palbociclib may reduce fertility in men.
For this reason, men should consider saving sperm before taking it.
on a way
Take the medicine once a day at about the same time, with or without food.
Swallow the tablet whole with a little water. Tablets should not be chewed or crushed. Tablets should not be broken before swallowing. Tablets that are broken, cracked, or otherwise damaged should not be taken.