Doxycycline buy – Key points
The spectrum of action of the drug on microbes is very wide.
The production of proteins in the microbial cell is inhibited, the connection between the 30S subunit of the ribosomal membrane and transport aminoacyl RNAs is disrupted.
In addition, doxycycline has a bacteriostatic effect.
Some Gram-positive organisms are very sensitive to doxycycline. These are primarily staphylococci, streptococci, listeria, anthrax pathogens, clostridia, actinomycetes.
Also, this antibiotic is effective against gram-negative microorganisms and intracellular pathogens. It is very effective against Haemophilus influenzae and granulocytic ehrlichiosis.
Shows high efficiency in the treatment of acute mycoplasmal bronchitis and pneumonia. If a patient under 65 years of age has no comorbidities, doxycycline can also be used. For elderly patients, this antibiotic effectively treats urinary tract infections and acute prostatitis.
Treatment of malaria is successful when doxycycline is combined with quinine.
Resistance to doxycycline is shown by viral and fungal infections, most bacteria from the genus Bacteroides, Serratia, proteus mirabilis and Pseudomonas aeruginosa.
Doxycycline can be purchased by patients as an alternative to penicillin if this drug is contraindicated for him.
Always read the package insert for doxycycline and if you have any questions about the effect or use of the product, consult your doctor or pharmacist.
Indications for use – what Doxycycline is used for
Among the indications for the use of Doxycycline, infectious pathologies that were caused by pathogenic agents sensitive to Doxycycline are distinguished. This group of pathogens includes:
Recurrent typhus epidemiological type (causative agent – Borrelia)
Non-gonococcal urethritis (causative agent – T-mycoplasma)
Uncomplicated rectal, endocervical and urethral infections (chlamydia)
With conjunctivitis with secretions, monotherapy is relevant, combined treatment with drugs that are applied topically is allowed.
Trachoma is not eliminated in all patients, but in some cases, treatment is effective.
Ornithosis (Chlamydia psittaci)
Lymphogranulomatosis
Respiratory infection (mycoplasma)
Tick-borne typhus, Rocky Mountain spotted fever, typhoid fever, Q fever.
Infectious pathologies caused by gram-negative microorganisms are also sensitive to doxycycline.
The antibiotic doxycycline is effective in the treatment of prostatitis, since approximately 30 minutes after application, the drug reaches the concentration necessary to destroy pathogens in the prostate. Not every antibiotic shows such a good interaction with plasma proteins. Treatment in this case is focused on the standard daily dosage – 2 tablets per day. In the absence of complications, treatment lasts one week.
Infections that can be treated with doxycycline include Gram-positive infections, anthrax, and upper respiratory tract infections.
Side effects
Cardiac disorders: tachycardia (rare)
Gastrointestinal disorders: heartburn, nausea, flatulence, steatorrhea, mild diarrhea, epigastric discomfort.
From the nervous system: rare cases of benign intracranial hypertension have been reported, which is reversible and is characterized by an increase in intracranial pressure, accompanied by headaches, nausea, vomiting, and possibly swelling of the optic nerve head. Violation or loss of smell and taste. This is only reversible in some cases. Reversibility is only partial. paresthesia
Diseases of the liver and biliary tract: an overdose of this antibiotic can cause liver damage and pancreatitis.
On the part of the skin and subcutaneous tissue: increased skin sensitivity to the sun can lead to phototoxic reactions on exposed skin, manifested by erythema, edema and blistering.
Therefore, during treatment with doxycycline, avoid sunbathing in nature or in a solarium.
Contraindication
An obstacle to taking this antibiotic are the following absolute contraindications:
Leukopenia and porphyria
malabsorption
Intolerance to lactose or the main active ingredient
Lactase deficiency
Severe liver failure is also a reason not to buy the antibiotic doxycycline or reduce the daily dose, otherwise the likelihood of a hepatotoxic effect is high.
doxycycline and alcohol
The simultaneous use of the antibiotic doxycycline and alcohol increases the toxic effect, which is manifested by headaches and dizziness. The same unpleasant effect has a small interval between taking the drug and alcohol.
Since both alcohol and doxycycline are broken down in the liver, their simultaneous use significantly increases the load on this organ, which can lead to the development of reactive hepatitis. Therefore, the simultaneous use of Doxycycline and alcohol is strictly prohibited, and after the end of therapy, alcohol can be consumed only after 35 hours.
Doxycycline and smoking
Smoking also affects the effectiveness of tetracycline antibiotic therapy, as cigarette smoke contains components that affect the liver and reduce the effectiveness of the drug. The absorption of the active substance slows down and the therapeutic effect is not only less pronounced, but also begins with a delay.
If you smoke regularly, the dose of the drug may be increased.
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